39 North, a new innovation district was announced on December 7, 2016.  The district includes 600 acres surrounding the Danforth Plant Science Center, BRDG Park, Helix Incubator, Yield Lab and Monsanto.  By connecting regional assets, improving mobility, creating development opportunities and additional greenspace will enhance the region’s ability to grow, attract and retain companies and top talent.


The 39 North Master Plan funded by a $500,000 grant from the U.S. Department of Commerce, presents a vision for  an innovation district in St. Louis County that is uniquely positioned to advance the region’s global leadership in plant and life sciences. The district will be geared toward lifestyle preferences often sought by highly-skilled employees, including mixed retail, residential and office space connected by walking and biking trails and green space. 

Community input was paramount to the process.  More than 45 meetings, focus group sessions and two community open houses were held to gather feedback from stakeholders including, scientists, residents, property owners and developers, elected officials, local businesses, the Missouri Water Company, the Missouri Department of Transportation and area educators for ideas to create a thriving district.

Five transformative goals were identified: 
  • Strengthen corridors and establish new traffic patterns
  • Connect assets and opportunity sites
  • Establish a cohesive development framework
  • Create a mixed-use center of activity
  • Communicate the district

In the near term, dedicated staff at the St. Louis Economic Development Partnership will manage implementation of the plan for 39 North in coordination with a steering committee of essential stakeholders, all of whom shaped the Master Plan. In the longer term, an empowered nonprofit entity will be created to ensure the continuation of the District’s mission.


Great Rivers Greenway awarded 39 North $400,000 to design an open space framework and biking and pedestrian paths that connect to the Centennial Greenway. The RFPs for Phase I of the design were collected and the review process is underway.  

Funding for the redesign of the Olive and Lindbergh Boulevard interchange has been secured with $4 million from the Federal Highway Administration and $1 million from St. Louis County.  

St. Louis County voted unanimously to approve $450,000 for preliminary planning for the redesign of Old Olive. The City of Creve Coeur is providing an additional $50,000. This funding will support the development of a Great Streets plan to give Old Olive a localized, main-street vibe. The Economic Development Partnership has issued a Request for Proposals (RFP) for an experienced and qualified planning/engineering firm or team to analyze the existing conditions of Old Olive Street and develop a design for the Project in accordance with the 39 North master plan. The RFP is available here.

Venture Café @ 39 North gatherings are held from 4 PM to 7:30 PM on the third Tuesday of every month (except December) at the Danforth Plant Science Center.  The gatherings facilitate serendipitous collisions that drive creativity, foster collaboration and stimulate investment in innovation. The event is free and open to the public.


Read the 39 North Master Plan
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